Discovery може да доведе до нови лекарствени лечения за Алцхаймер и затлъстяване
Изследователите се надяват откриването на нов клас молекули да докара до създаване на целеви лекарствени лекувания за възпалителни болести като Алцхаймер, астма, артрит и затлъстяване.
Проучване, водещо от университета на кралица diseases.
The study was co-led by Dr Rebecca Coll from the Wellcome-Wolfson Institute for Experimental Medicine (WWIEM) at Queen’s and Dr Kevin Wilhelmsen from BioAge Labs, the US biotech company which discovered the new class of molecules.
The researchers studied inflammation within the body which persists for a long time and the immune response ends up damaging healthy cells, Тъканите и органи. this process to stop disease from developing and worsening.
Research over the last 20 years has shown that a protein complex called the NLRP3 inflammasome plays a key role in causing damaging inflammation in many of these diseases.
Whilst previous clinical trials have tested molecules that restrict NLRP3 activity, the new stud...
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